ATP-binding cassette (ABC) transporters are highly expressed by brain endothelial cells that form the blood-brain Exfoliator barrier (BBB).These efflux pumps play an important role in maintaining brain homeostasis as they actively hinder the entry of unwanted blood-derived compounds into the central nervous system (CNS).Consequently, their high act
Background.Posterior fossa epidural hematomas represent 7-14% of all traumatic intracranial epidural hematomas.They are most frequently encountered posttraumatic mass lesions in the posterior fossa.The aim of this study was to identify clinical features that could lead to the early diagnosis of posterior fossa epidural hematoma.Methods.Between 1980
Thymic gland (thymus) represents a huge mystery for biology, medicine (primarily immunology), including pediatric issues.Complexity of the study is determined by the multiplicity of integral connections of Footwear thymus with other components of immune system, neuroendocrine, hematopoietic systems, connective tissue, different organs and cells whi
Oxygen is essential to all the aerobic organisms.However, during normal development, disease and homeostasis, organisms are often challenged by hypoxia (oxygen deprivation).Hypoxia-inducible transcription factors Hand Sanitiser (HIFs) are master regulators of hypoxia response and are evolutionarily conserved in metazoans.The homolog of HIF in the g
We Teen Multiples report the case of a 58-year-old female presenting with central airway obstruction leading to airway compromise thrice, first two times from endobronchial growth of typical carcinoid tissue and subsequently from granulation tissue at anastomotic site after left carinal pneumonectomy.Bronchoscopic resection of carcinoid tumor and g